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Seroquel (quetiapine fumarate)
Overall Rating
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5.58
Rating:

5.58

Side Effects
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4.32
Pricing
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4.12
Average Price: $49.84 Thumbs up Recommended By
72% of reviewers (of 79 reviews)
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Seroquel®

Generic Name: Quetiapine Fumarate kwe-TYE-a-peen & FU-ma-rate

Drug Class: Antipsychotics

 

Contents

 

Description
This medicine is classified as an antipsychotic medication and is used to treat patients that suffer from delusions, hallucinations, unorganized thought and hostility. This medicine may also be prescribed to treat severe behavioral problems in children.
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General Information
This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. 

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Proper use of this medicine
Take this medicine exactly as directed by your doctor or pharmacist. This medicine should be taken continually, even if you are feeling better. Follow the directions on your prescription label. Do not take more or less of this medicine that prescribed. Do not share this medicine with other people.
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Missed Dose
Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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Storage
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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Possible Side Effects
    • Check with your doctor AS SOON AS POSSIBLE if you experience diarrhea, vomiting, unsteadiness, difficulty walking, or unusual muscle weakness.
    • This medicine can cause the following side effects:
      • contipation
      • dizziness
      • drowsiness
      • dry mouth
      • headache
      • weight gain
      • restlessness
      • mild thirst
      • frequent urination
      • drowsiness
      • fine hand tremor
      • mild nausea
    • This medicine may increase blood sugar (hyperglycemia). Diabetic patients should be cautious of this and regularly check their blood sugar.
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Warnings/Precautions
    • Several days to weeks may pass before you feel the the full effects of this medicine.
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Overdose
Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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Drug Interactions
    • Let your doctor know if you are taking any of the following types of medications:
      • antacids
      • antihistamines
      • diet pills
      • benztropine (Cogentin)
      • bromocriptine (Parlodel)
      • carbamazepine (Tegretol)
      • dicyclomine (Bentyl)
      • fluoxetine (Prozac)
      • guanethidine (Ismelin)
      • lithium
      • meperidine (Demerol)
      • methyldopa (Aldomet)
      • phenytoin (Dilantin)
      • propranolol (Inderal)
      • sedatives
      • trihexyphenidyl (Artane)
      • valproic acid (Depakene)
      • cold medications
      • medications for depression
      • vitamins and herbs
    • Inform your doctor of all the medications you may use (both prescription and nonprescription), especially if you are taking any of the following:
      • anti-depressant
      • anti-anxiety drugs
      • sparfloxacin
      • grepafloxacin

      • guanethidine
      • guanadrel
      • lithium
      • metrizamide
      • cabergoline

      • tranquilizers
      • barbiturates
      • sleeping pills
      • narcotic pain
        medication (e.g. codeine)
      • other medicines that make you drowsy.
    • Many cough-and-cold products contain ingredients that may add a drowsiness effect. Before you use cough-and-cold medications, ask your doctor or pharmacist about the safe use of those products..

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Pregnancy/Nursing
Tell your doctor if you are pregnant or planning to become pregnant. For women: since this medicine is excreted in human breast milk, you should NOT breastfeed while taking this medicine.
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More Information

For more information about this medicine, talk to your healthcare provider.
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Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com
This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.



Last reviewed:

  On 8 Aug 2006

  By John M. Grohol, Psy.D.





 

seroquel

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jennie
Grand Poohbah


Registered: December 2002
Posts: 1939
Review Date: Thu June 22, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 1 

 
Positive aspects of this (pros): none
Negative aspects of this (cons): forgetfulness * confusion * tardive dyskinesia

Thumbs Down! Increased dosage caused forgetfulness which caused me to miss a few doses. I called the doc and had this medication adjusted again. Next thing I know I was locked up in the psych ward, confused, and had a medication-induced psychosis.

If you take this drug, please be very careful taking this medication and have a pill organizer. You should also be monitored closely by your prescribing physician, counselor, family, and/or significant other.

I do not recommend antipsychotics for anyone.

niko851
Member


Registered: March 2006
Posts: 82
Review Date: Tue July 25, 2006 Would you recommend this? Yes | Total Spent: $160.00| Rating: 3 

 
Positive aspects of this (pros): Has somewhat reduced the # or severity of my manic states
Negative aspects of this (cons): KNOCKS YOU OUT, confusion (more-so than already), forgetfullness, VERY EXPENSIVE

This medicine is supposed to prevent psychotic episodes - or at least aleviate some of them - but I still have them. It is a guaranteed sleep medication for me - within a half hour, I am out and if I am woken up, I'm in the thickest fog imaginable. I become more forgetful than I already am and I am much more confused. Granted, I'd rather be 'catatonic' than raging, but I surely did not ask to become 'zombied out'.
Sarah116
Grand Poohbah


Registered: August 2006
Posts: 1623
Review Date: Tue August 8, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 2 

 
Positive aspects of this (pros): -
Negative aspects of this (cons): -

After getting started on it I had nasty side efffects and it did nothing! Depression, severe weight gain, headaches, makes veins, face and skin very nasty! Dizzy, faint feeling, extreme loss of contact with body (felt like I had a really nasty case of the flu or maybe even Autism.)
Used it for Schizotypal!
Daffy
Visitor

Registered: August 2006
Posts: 2
Review Date: Tue August 15, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 7 

 
Positive aspects of this (pros): Levels out mixed states
Negative aspects of this (cons): Sleep much of the day's

this is a good med with the exception of gained weight and wanting to sleep all the time
bigdog1263
Member

Registered: September 2006
Posts: 28
Review Date: Mon September 11, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 4 

 
Positive aspects of this (pros): small doses good as a sleep aid
Negative aspects of this (cons): larger doses seem to fan the flames of my manic episode

terrible side effects, weight gain potential
JustAPixie
Elder


Registered: July 2006
Posts: 5176
Review Date: Wed September 13, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros):
Negative aspects of this (cons): disoriented, confused extremely drowsy, depressed

I have major depression and used seroquel to get some rest at night. I can't say I won't recommend it for others because I don't know. It made me too drowsy and I couldn't get up in the mornings. I was also very confused while on it and it only made my depression worse.
eskielover
Magnate


Registered: October 2004
Posts: 2486
Review Date: Thu September 14, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): helps control anxiety level, controls nightmares
Negative aspects of this (cons): difficult waking up after taking it.

I am provided this med from my pdoc's samples. I take it when my anxiety level is high & it helps best if I can just lay down & sleep off the anxiety attack. If I take a high dose, it is harder to wake up immediately & can be drowsy most of the day. It helps me go into a deep sleep to avoid the nightmares from the PTSD. During the day, if anxiety is high, a low dose helps keep me calm & can still function most of the time. I don't think it would be a good solution if I had a job due to the drowsyness. It was the replacement for thorazine when I had a bad reaction to it. I have been lucky to avoid a similar reaction with this med. I do have a hard time functioning when I need to take a larger dose of seroquel, but it has helped me through the PTSD symptoms I have been dealing with.
PasDeDeux
Grand Member


Registered: July 2006
Posts: 810
Review Date: Thu September 14, 2006 Would you recommend this? No | Total Spent: $3.00| Rating: 1 

 
Positive aspects of this (pros): none
Negative aspects of this (cons): can cause diabetes, and movement disorders as well as parkinson LIKE issues

I was given this for a sleep issue and didn't sleep much better but was very apathetic, flat affect, I did NOT eat much....I just sat till it wore off. I also had heart palpitations on it. I didn't like it at all and feel it should not be given unless one has a psychotic issue.
endless_hysteria
New Member


Registered: October 2006
Posts: 5
Review Date: Thu October 5, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 6 

 
Positive aspects of this (pros):
Negative aspects of this (cons):

i have mixed feelings about this drug. it made me feel great, got rid of all my "dark thoughts" but i did have a severe manic episode while taking them, much worse than usual.
ccpaz
Visitor


Registered: October 2006
Posts: 3
Review Date: Tue October 24, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 1 

 
Positive aspects of this (pros): oh?
Negative aspects of this (cons): nightmares, downer, counter acted the effect of caffeine

I don't know how to explain this med well. It was provided to me by a health physician as a sleeping aide who thought that I may be bipolar the day she first met me. This stuff KNOCKED me out moments after i'd take them, then i'd have paranoid sleep and always had a hard time waking up out of a nightmare (usually after skipping a night) -- i took this stuff for about 2 weeks. When I told my physician, she told me not to skip and doubled my dose, hallejuah. So on the double dose i was so depressed I felt like killing myself so i bought a 5 shot mocha frap and never felt so depressed in my life. I ended up leaving work early and scheduled to meet with an actaul psychiatrist.
Review Date: Thu November 2, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): helpful for anxiety
Negative aspects of this (cons): can take some time to adjust to and affect sleep quality

I was on 250mg of this 2x daily for a few years... I found it to be pretty good. It numbed my feelings basically, which was what I wanted. I stopped taking it because I was concerned about it affecting my cognition (starting back at school). Since then I've thought about going back on it and I have started taking it a couple of times. Each time I started I started on 50mg in the evening. I found it affected my quality of sleep (negatively). I would be zonked out (didn't wake up for a fire alarm) and I felt really groggy the next morning. It would also zonk me out at night within one hour. It takes around one week for your system to adjust to it. I found it to be fairly helpful but I'm concerned about not waking up for fire alarms so I'm not taking that one any more! That being said if I'm having a really hard time of it 50mg of Seroquel is a useful alternative to a benzo...
les61051
Visitor

Registered: November 2006
Posts: 1
Review Date: Fri November 3, 2006 Would you recommend this? Yes | Total Spent: $329.00| Rating: 6 

 
Positive aspects of this (pros): this drug has made my sleepness night much better. the rapid thoughts have deceased incredibly
Negative aspects of this (cons): You feel like your a zombie--but to me, sometimes that is ok--quite sedating

Has made my horrible anxiety and increased aggression and emotional ups and down (I am a rapid cycler) more tolerable. I am not saying it is the greatest drug in the world, but I will say I do sleep better now, decision making has been better. My manic episodes have decreased, although when I get depressed I really get depressed. I can't take an antidepressant as part of my drug regeime because they cause extreme mania. Lamictal is for the stabalizing effect and Klonopin for the horrible anxiety I feel.
kim7
Visitor

Registered: November 2006
Posts: 8
Review Date: Sat November 4, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): worked but...
Negative aspects of this (cons): Slept a lot, zombie-like, forgetful

Worked well, but the side affects weren't worth it.
jenncsw
Visitor

Registered: November 2006
Posts: 1
Review Date: Fri November 10, 2006 Would you recommend this? Yes | Total Spent: $30.00| Rating: 9 

 
Positive aspects of this (pros): keeps away most negative symptoms of bipolar
Negative aspects of this (cons): expensive

I have bipolar I, with psychosis. This is the only med that has ever helped with hallucinations and paranoia. I think it works way better than the lithium cr that I take. The lithium has so many side effects.
Seroquel's main side effect that I have noticed is tiredness, and the weight gain that goes with it.
Also, the actual price without insurance would be prohibitably expensive.
I have not tried any other antipsychotics but this one does work well for me.
mcclt733
Visitor

Registered: November 2006
Posts: 1
Review Date: Tue November 21, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 7 

 
Positive aspects of this (pros): It does put you to sleep
Negative aspects of this (cons): I eat like crazy, I've gained a great deal of weight

I've been taking this for about a year and half now, and it does knock you out it does leave you dis-oriented should you wake up in the middle of the night & I sleepy all the time, but I also have to say that I 4 other drugs for depression,zoloft 200mg,mirtazapine 45mg,(buspirone 60mg,hydroxyzine 100mg,these are for anxiety),and to honest all of these have made me more withdrawn, not that I mind, I like being by myself.
Xilber
Visitor

Registered: December 2006
Posts: 3
Review Date: Fri December 1, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): great sleep, possible mood elevation
Negative aspects of this (cons): drowsy upon waking

Along with Lithium, took 100mg at night, and for the first few weeks it forced me to bed soon after taking it. Gradually I was able to stay up a few hours in a drowsy state. Sleep was very deep, I never once woke up during the night. Takes a while to get going in the morning. I sensed a slight improvement in my mood, but not much. Did not help with irritability I had been having.
crazymusiclvr
Member

Registered: January 2006
Posts: 71
Review Date: Sat December 2, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 9 

 
Positive aspects of this (pros): Helps with mood. I get quality sleep
Negative aspects of this (cons): I have to take a different dose every night as the effects can vary daily.

This medication has saved me. It is expensive but it has helped with my elevated moods and I use it mainly as a sleep aid. I have been dreaming for the first time in a long time when I take it which means i'm getting better quality of sleep. I take between 300mg and 400mg before bed. The only weird part is I have to take a 100mg, wait an hour and see how it effects me because it's important not to take more than you need and it seems to affect me differently every day depending on my mood. It did take about 2 months to get used to this medication so give it time.
Chamshroin
Visitor

Registered: December 2006
Posts: 1
Review Date: Tue December 12, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 3 

 
Positive aspects of this (pros):
Negative aspects of this (cons): Diabetes side effect

I have great concerns about this medicine. FDA has issued a warning letter to the AstraZeneca company for its misleading material in regards to the risk of developing diabetes and related health iusses.

Read the article

My 12 year old son, took seroquel 100 mg TID for a total of 300 mg a day - the recomended doesage - for less than six months. We are now faced with a life of diabetes related health issues.

Be warned - of the risks assocated with this medicine.

undertheradar
Member


Registered: December 2006
Posts: 100
Review Date: Fri December 22, 2006 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): helps me sleep 7-8 hours a night
Negative aspects of this (cons): daytime agitation

My pdoc put me on 150mg nightly to help me sleep and stabilize mood. I was taking it during the daytime and it would make me more agitated than I already was. I don't recommend it for day, but night is good
swell
Visitor

Registered: December 2006
Posts: 3
Review Date: Sat December 30, 2006 Would you recommend this? No | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): helped with sleep
Negative aspects of this (cons): extreme bloating/ weight gain

Its hard to determine all the positive aspects since I was on other medications. As soon as I started the treatment I gained nearly 40 lbs. People mistakenly thought I was pregnant. My sister too had the same exact side effects. As soon as I came off the bloating came down and so did some of the weight.
wally
Member

Registered: December 2006
Posts: 91
Review Date: Tue January 2, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 5 

 
Positive aspects of this (pros): Used to help with sleep
Negative aspects of this (cons): extreme drowsiness and dizziness

I just started this medication about a week ago. I am in an acute stage of hypomania and this medication does put me to sleep. However, it knocks me out and I find it difficult to keep up physically with my racing thoughts and even coffee has little effect in waking me now in the mornings. That being said, the verdict for me,is still out.
dooris
Visitor

Registered: November 2006
Posts: 3
Review Date: Sun January 14, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 4 

 
Positive aspects of this (pros): helps with sleep
Negative aspects of this (cons): i'm confused, tired and have lost my appetite, dry mouth and nose, nose bleeding

I have bipolar with mild psychotic mania. Seroquel 300mg nightly.
tommy_boy
Visitor


Registered: January 2007
Posts: 1
Review Date: Thu January 18, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 6 

 
Positive aspects of this (pros): great for sleep
Negative aspects of this (cons): very tired/hard to go in the morning

Definetly gives me some peace in my head,along with a good nights sleep. Have had a mild back ache since i have started on this drug. Doc. says its nothing to worry about though. Still have very much anger and agitation within just to tired to care. Has helped with other symtoms, somewhat leveled off for a couple of months.
FlashDuck
Visitor


Registered: February 2007
Posts: 1
Review Date: Tue February 6, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 10 

 
Positive aspects of this (pros): Works for me!
Negative aspects of this (cons): Would be very expensive if on a high dose

I am on the minimum dose (25mg at night) and find that it is perfect for me.

It allows me to sleep with few discernable side effects, and perhaps more importantly, removes the intrusive nightmares, images and thoughts that plague me with PTSD.

To date (about 6-8 months) I have not noticed a dose related dependence or need to increase for the same effect. On the occasions that I have missed it, or take it too late in the evening (I find that around 7pm for a 10pm bed time), difficulties in falling asleep and 'bad thoughts' return.

Maybe not for everyone, but I'm a convert.

dukat
Visitor

Registered: November 2006
Posts: 2
Review Date: Fri February 23, 2007 Would you recommend this? Yes | Total Spent: $60.00| Rating: 5 

 
Positive aspects of this (pros): Helped me sleep for the first few years of using it.
Negative aspects of this (cons): Weight gain, heat strokes, akathesia

This stopped working after 5 years at 600mg/night.
Voices came back stronger than ever. I also took Wellbutrin SR, lorazepan, Depakote, Neurontin, Benadryl, Verapamil, Atenolol, Trazadone, Artane, and Ambien. All at the same time, so it was hard to tell which drug was causing which problem.
I have been slowly reducing the meds on my own since no doc will help.
I hate sie effects! They are worse than the illness!
ifwinterends
Junior Member

Registered: December 2006
Posts: 15
Review Date: Sun February 25, 2007 Would you recommend this? No | Total Spent: Not Indicated| Rating: 4 

 
Positive aspects of this (pros): knocks you out fairly quickly
Negative aspects of this (cons): tired all day, inability to dream, weight gain

I was given this for insomnia and nightmares related to PTSD. For the first few months it worked great. I slept the whole night through and got to sleep quickly, as compared to lying awake at 3am and waking frequently. After a year, the side effects kicked in. I woke up a few times to hallucinations similar to those experienced on Ketamine (possibly a flash-back), went from weighing 120 to 145 quickly, and became entirely apathetic (I used to be an artist and musician, now I have no passion for either). So I would only recommend this for a few month's good sleep.
Sikboy
Visitor


Registered: February 2007
Posts: 1
Review Date: Mon February 26, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 0 

 
Positive aspects of this (pros):
Negative aspects of this (cons):

I would like to ask, is the weight gain on quetiapine fat gain or water weight gain? Does the drug make you crave foods more?

Thanks.

boomslang
Member

Registered: February 2007
Posts: 20
Review Date: Wed February 28, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 2 

 
Positive aspects of this (pros): Knocks me out so stops a manic episode
Negative aspects of this (cons): Takes awhile to kick in (up to an hour) so manic episodes have already wrecked havoc

1year, 2 months

250mg now down to 150/day

Side effects:
EXTREME drowsiness
Confusion/Paranoia/Groggy/Almost complete loss of short-term memory
Fast heart rate/Heart arrythmias
Shortness of breath
Mad Munchies (which will make you gain weight - though I haven't gained any b/c my metabolism is very fast)

It did it's job while I was on it but I am now in search for a better med. The 'job' I am referring to is to knock-you-out so you don't do or think crazy things. It basically is designed to sedate you enough so you cannot function.

------------------------------
March 16, 2008

I am now on Lamictal 200mg 2x day, Fluphenazine 1mg morning 2mg night, Xanax XR 1mg/day, Ativan 0.5mg night, and Focalin XR 20mg morning, for Bipolar I, ADHD, Tourrete's Syndrome, and Anxiety. I no longer take Seroquel. I stopped taking it back in January of 2007 because I went Paramedic school and could not think while on it. Thank god I stopped seroquel. I now have a full time job as a Paramedic and have had one since December 4th 2007. I am a certified Paramedic. I have completed both EMT-Basic (Jan-July 07, and EMT-Paramedic, March-Dec 07). Now I work 2-3x 24 hour shifts a week saving people's lives. I just want to let you know that there is hope for you when you are down. I was in a deep dark horrific place for over 2 years and now I am doing great! I wish the best for you!

loupopeye22
Visitor

Registered: March 2007
Posts: 10
Review Date: Tue March 20, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 9 

 
Positive aspects of this (pros): reduces pychosis/manic depressive symptoms
Negative aspects of this (cons): tiredness in the mornings

helps to reduce psychosis/manic depressive symptoms also concentration have been improved a lot since started the meds. Sleep patterns are much better now than before but eating habits aren't getting any better as I have eaten too much choccy now than ever cos the taste is so so lovier as in paradise!
lisad
Junior Member


Registered: February 2007
Posts: 11
Review Date: Mon March 26, 2007 Would you recommend this? Yes | Total Spent: $3.35| Rating: 8 

 
Positive aspects of this (pros): Not as cranky or moody... makes me feel evened out
Negative aspects of this (cons): 200 and I sleep like a baby... but it stays with me til early afternoon

I'll probably like it more when we get an antidepressant added that doesn't cause me to stay up for most of a weekend.
darklands
Visitor

Registered: April 2007
Posts: 1
Review Date: Thu April 5, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): Helped calm my rapid cycling, took the edge off the depression, helped combat negative effects of other antideppressants
Negative aspects of this (cons): intense drowsiness for the first couple weeks, increased appitite

After starting prozac i started cycling rapidly between acute mania and intense depression with psychosis. I would switch up to 8 times a day. It was very exhausting and debilitating. I started Seroquel at 100mg a day. I currently take 700mg after taking it for two months. It really helped stop the intense, troubling cycling and helped me get back to functioning properly. I am currently taking zoloft to help with depression. The Seroquel really helps with the negative side effects (more intense mania and anxiety associated with use of ssri's in bipolar patients) and makes it bearable.
romosexual
Visitor

Registered: April 2007
Posts: 2
Review Date: Thu April 12, 2007 Would you recommend this? Yes | Total Spent: Not Indicated| Rating: 8 

 
Positive aspects of this (pros): Takes care of most of my manic and depression episodes
Negative aspects of this (cons):