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Overall Rating
6.22
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Rating:
6.22
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Side Effects
6.21
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Pricing
9.30
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Average Price: $4.83
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Recommended By
63% of reviewers
(of 27 reviews)
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advertisement
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Desyrel®
Generic Name: Trazodone TRAZ-oh-done
Drug Class: Antidepressants, miscellaneous | | Contents | Description | This medicine is used for treatment of depression. Your doctor may have prescribed this medicine to help relieve, anxiety, tension or to help you sleep. Your doctor may have prescribed this medicine for other conditions as well.
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| | General Information | | This information is for educational purposes only. Not every known side effect, adverse effect, or drug interaction is in this database. If you have questions about your medicines, talk to your healthcare provider. Top of page
| | Proper use of this medicine | Follow the directions given to by your doctor. This medicine should be taken orally on a regular basis. It is best that that you take this medicine at bedtime unless otherwise directed by your doctor. The extended-release tablet and capsule should be swallowed whole. Do not chew, divide, or crush the extended-release tablet or capsule.
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| | Missed Dose | Take your next dose as soon as you remember. If it is time for your next dose, skip the missed dose and go back to your regular schedule. Do not double doses.
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| | Storage | Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture. Throw away any medication that is outdated or no longer needed.
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| | Possible Side Effects | - dizziness, drowsiness
- agitation, confusion
- Consult your doctor immediately if you experience prolonged and painful erections.
- Expected side effects are increased appetite and weight gain.
- drowsiness, fatigue, dizziness
- dry mouth
- Unreported side effects are possible, talk to your healthcare provider if any other symptoms occur.
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| | Warnings/Precautions | - Do NOT stop taking this medicine abruptly.
- This medicine may cause dizziness or drowsiness.
- Alcoholic beverages can increase the effects of this medicine and should be avoided.
- Don't drive or perform other tasks that require concentration, until you know how this medicine affects you.
- This medicine can increase the risk of suicidal thinking and behavior in some children and teens. Parents of children taking antidepressants should watch for signs of worsening depression or unusual changes in behavior.
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| | Overdose | Seek medical attention immediately. U.S. residents can call the national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly.
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| | Drug Interactions | - Before taking any new prescription or over-the-counter medication, talk to your doctor or pharmacist.
Taking this medicine together with diazepam (Valium) may impair movement ability.
Avoid using this medicine with MAO inhibitors. Your doctor or pharmacist can tell you if you are taking an MAO inhibitor.
- Talk to your doctor if you are taking certain antibiotics such as erythromycin, clarithromycin or azithromycin. This medicine should not be taken with MAO inhibitors.
- Let your doctor know if you are taking any vitamin supplements or herbal products. St. John’s Wort should be avoided while taking fluvoxamine due to the increased side effects of too much serotonin.
- MAO inhibitors should not be taken while taking the following drugs:
- Tell your doctor if you are taking other antidepressants, medications for blood pressure, medications for diabetes, sleeping pills, tranquilizers, vitamins or herbs.
- This medicine may increase the affects antihypertensive drugs, drugs with sedative effects, phenytoin (Dilantin) or fosphenytoin (Celebyx) and tramadol (Ultram).
- Do not take MAO inhibitors type A with this medicine. If you are not sure if you are taking an MAO inhibitor, talk to your doctor or pharmacist. Certain other antidepressants, clozapine (Clozaril), haloperidol (Haldol), lithium, trazadone, and others may increase the risk of seizures. BEFORE taking any new prescription or over-the-counter medicine, talk to your health care provider.
- Patients taking MAO inhibitors should not be take this medicine.
- Nafazodone can decrease the effects of clonidine, methyldopa, diuretics (water pills), warfarin and drugs used to lower blood sugar (hypoglycemics). This medicine can increase the toxic effects of; terfenadine, astemizole, fluoxetine (Prozac), triazolam, alprazolam (Xanax) and phenytoin (Dilantin). Do not take this medicine within 14 days of stopping MAO inhibitors. If you are not sure what an MAO inhibitor is, talk to your doctor or pharmacist. If you are currently taking any of these medicines, talk to your doctor or pharmacist to see if Nefazodone is right for you.
- Possible drug interactions may occur with phenobarbital causing a decrease in the effect of the medications. Severe blood pressure problems and seizure can occur with taken with MAO inhibitors.
- Talk with your physician or pharmacist if you are taking other medications.
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| | Pregnancy/Nursing | If you are pregnant or thinking of becoming pregnant, before taking this medicine talk to your doctor about the benefits versus the risks to your pregnancy.
In testing with animals, studies show delayed bone development. Use this medicine only if it clearly necessary. It is advised not to take this medicine while nursing. If you have any concerns, talk to your doctor or pharmacist.
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| | More Information | Antidepressant medications are used to treat a variety of conditions, including depression and other mental/mood disorders. These medications can help prevent suicidal thoughts/attempts and provide other benefits. However, studies have shown that a small number of people (especially children/teenages) who take antidepressants for any condition may experience worsening depression, other mental/mood symptoms, or suicidal thoughts/attempts. Therefore, it is very important to talk with a doctor about the risks and benefits of antidepressant medication, even if the treatment is not for a mental condition. Tell your doctor immediatley if you notice worsening depression, unusual behavior changes, (including possible suicidal thoughts/attempts), or other mental/mood changes. Be especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.
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| Copyright 2006 PharmClips, Inc. All rights reserved. www.pharmclips.com | This information is not intended to cover all possible uses, directions, precautions, drug interactions, or adverse effects. This is general information and should not in any event be construed as specific instructions for individual patients. The publisher does not accept any responsibility for the accuracy of the information or the consequences arising from the application, use, or misuse of any of the information contained herein, including any injury and/or damage to any person or property as a matter of product liability, negligence, or otherwise. No warranty, expressed or implied, is made in regard to the contents of this material. The reader is advised to check with their health care provider before making any changes in their drug regimen.
Last reviewed:
On 8 Aug 2006
By John M. Grohol, Psy.D.
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Reviews
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jennie
Poohbah
Registered: December 2002
Location: DC metro area
Posts: 1341
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Review Date: Thu June 22, 2006
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 3
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Pros:
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excessive sleep
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Cons:
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excessive daytime drowsiness * impaired driving
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I was prescribed Desyrel to help with my sleep disturbances for PTSD. I think prescribing Desyrel along with other antidepressants and antianxiety meds is a common practice of psychiatrists. I think doing such intoxicates patients too severely and prevents normal functioning at work and prevents independence (such as driving). I also think other sleep disorders may be overlooked. I had undiagnosed sleep apnea at the time I was taking Desyrel.
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candybear
Grand Magnate
Managing Editor, PC
Registered: April 2004
Location: the frozen tundra
Posts: 4312
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Review Date: Fri September 8, 2006
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 7
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Pros:
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puts you to sleep
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Cons:
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makes you excessively groggy
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I've tried this one (aka Trazodone) twice. First time, worked great for a long time (if you overlook the walking-into-walls thing when you wake up unexpectedly!). Second time, didn't touch me. I had to pick yes or no, so I picked yes, but my review would actually be a middling "eh."
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eskielover
Magnate
Registered: October 2004
Location: Harrodsburg, Kentucky, USA
Posts: 2395
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Review Date: Thu September 14, 2006
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 3
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Pros:
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Cons:
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dizziness, migraine pain, sleepiness
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This medication was given under hospital evaluation. This medication effected my blood pressure, causing dizziness. The migraine pain showed up within the first 8 hours (upon waking up the next morning). On top of these reactions to the med, I found that sleepiness was another effect that is caused.....unable to stay awake after taking it.....extremely drowsy. Due to the side effects, I wasn't able to stay on the med long enough to determine is it had any effect on my depression
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darkeyes
Moderator
Community Support Team
Registered: May 2001
Location: US
Posts: 6595
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Review Date: Fri September 15, 2006
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 1
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Pros:
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may help relax one enough to fall right to sleep,sort of like a sleeping pill effect
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Cons:
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Only took once,gave me a huge migraine headache and made me feel like I was anesthetized
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This medication may help others,but didn't have any positive effects on me.
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abilifyguy
Member
Registered: November 2006
Location: Memphis, TN
Posts: 68
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Review Date: Wed November 1, 2006
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 10
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Pros:
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Good sleep aid, great anti-anxiety aid
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Cons:
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initial headaches - but they go away with time
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I take this drug (100mg at bedtime) to cure insomnia caused by abilify. It is a great sleep aid with no daytime drowsiness. What I have noticed during the day is less anxiety and stress, especially at work. When I first started taking it I had some bad headaches, but that wore off in about a week.
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Brookester
Member
Registered: December 2006
Location: California
Posts: 47
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Review Date: Thu December 21, 2006
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 3
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Pros:
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makes one unconscious so they cannot complain
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Cons:
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excessive drowsiness
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this is a great med if you don't have anything to do the first 8 hours of the next day, because your brain is literally fried.
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Suzy5654
Poohbah
Registered: May 2006
Location: Indiana
Posts: 1155
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Review Date: Sun January 21, 2007
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 10
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Pros:
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I take it at night to help me sleep plus the anti depressant effects are helping
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Cons:
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none--no headaches; blood pressure still good on meds prescribed for that
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I was in a manic state when I was switched from Xanax at night (wasn't helping me sleep more than 3 hours) to Trazodone. Trazodone allows me to sleep for 6 hours. I don't have any daytime grogginess, but I do take Concerta & Provigil in the morning--both stimulants.
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Hopefull
Grand Member
Registered: November 2005
Posts: 732
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Review Date: Thu January 25, 2007
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 2
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Pros:
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It made me feel oddly sane when I woke up in the middle of the night. It lowered anxiety levels and improved mood in early morning.
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Cons:
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It didn't help me sleep and I was dizzy when I woke up in the middle of the night. I think I crashed in the middle of the day from it. But, it might have been the problem.
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I threw it away instead of taking it. Bleck!
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jattitude74
Member
Registered: March 2007
Posts: 124
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Review Date: Wed April 4, 2007
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 7
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Pros:
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helps with sleep and antidepressant effect helped
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Cons:
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loopy if I wake up in the middle of the night
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has worked well for me so far, started it for depression, then pdoc continued with it when i was diagnosed with bipolar, been on for 6 mo.
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DoubtingThomasina
Junior Member
Registered: April 2007
Location: North Dakota, ASA
Posts: 13
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Review Date: Wed April 11, 2007
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Would you recommend the product? Yes |
Total Spent: $12.00| Rating: 8
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Pros:
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Effectively treats insomnia
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Cons:
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May have to take it for a long time to stabilize sleep patterns
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Trazodone knocks you out in about 20 minutes. Waking up can be a little hassle but when you do, you are so well rested. It also helps treat depression in conjuction with other antidepressants. Bipolar people should be careful so as not to get manic. Mood stabilizers are also needed. This is my experience with Trazodone.
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marshall
Newly Joined
Registered: April 2007
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Review Date: Sun April 15, 2007
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 8
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Pros:
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Effective temporary sleeping aid, withdrawal is easy (unlike benzos and sleeping pills)
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Cons:
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Can be hard to get up the next morning.
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Trazodone is very helpful for getting a good nights rest if you are experiencing nightime anxiety. It will make you a bit dizzy and light headed if you try to stay awake on it, however I'm usually knocked out within an hour and those side effects are gone by morning.
Nothing bad happens to me if I miss a dose or quit "cold turkey". I can just take it as needed. This was not the case with Xanax which caused me a bit of trouble when I tried to quit.
Warning: Don't take any later than 7 hours before you have to get up or you might just sleep through your alarm!
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ouch
Veteran Member
Registered: June 2006
Posts: 321
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Review Date: Sun May 20, 2007
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 3
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Pros:
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helps with sleep, sex drive better, lifts mood when together with anti-dep
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Cons:
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excessive sleepiness during day
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Made me very tired during the day.
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tranquility
Grand Member
Registered: May 2007
Location: Rhode Island
Posts: 805
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Review Date: Tue May 22, 2007
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Would you recommend the product? Yes |
Total Spent: $7.00| Rating: 8
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Pros:
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good for sleep
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Cons:
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no negative if you take right when ready to go to bed
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taking trazadone for sleep for over 15 years. I fall asleep but would have trouble staying asleep. This keeps me asleep. Initially,a doc put me on this as a regular antidepressent about 17 years ago - 350 mg in the morning! That was not good - had to sit in a chair for 20 minutes until the room stopped spinning. would only recommend this for sleep:)
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EnigmaCat
Newly Joined
Registered: March 2007
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Review Date: Wed June 6, 2007
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Would you recommend the product? Yes |
Total Spent: $0.13| Rating: 10
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Pros:
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great sleep aid. really helps with anxiety. works well with fluoxetine to fight depression.
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Cons:
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when taken at bedtime, there are none beyond walking like a drunken sailor before fully awake.
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I'm currently taking 75 mgs of Trazodone a night right before bed. It has enabled me to get 8 hours of uninterupted sleep each night. I hadn't had that for years. It is also working quite well to alleviate my anxiety disorders, both during the night and throughout the day. My chief anti-depressant is fluoxetine (prozac). The trazodone is enhancing the effects of that medication.
The only con I've experienced is quite mild. When first rising, I'm a bit unsteady on my feet. That goes away in a minute or two.
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Sultrysorrow
Member
Registered: October 2007
Location: North Carolina
Posts: 41
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Review Date: Wed October 3, 2007
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 8
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Pros:
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Much better than Ambien or any OTC I've ever taken
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Cons:
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Takes a couple of hours to really kick in
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Since I've had bad episodes with hyponotics (medicated induced amnesia & hypnotic episodes not knowing what I was doing while awake) very scary. I was offered this medication by my psychiatrist to help me w/ my chronic rythmic movement sleep disorder and insomnia. I wouldn't consider taking anything else at this time in my life. I fall asleep and if I have to get up to go the the bathroom or whatever I have no problem falling back to sleep. Current dosage is 100mg.
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50guy
Veteran Member
Registered: February 2007
Location: Lakeville, MN
Posts: 469
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Review Date: Tue October 23, 2007
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Would you recommend the product? Yes |
Total Spent: $0.06| Rating: 8
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Pros:
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Helps you fall asleep faster.
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Cons:
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Takes more than an hour to work, sometimes up to 2 hours
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I take 100mg for insomnia. Sometimes I have weird dreams but, not scary ones.
Using it instead of Zoloft for relief in the daytime. It helps me stay asleep and I am calm during the day.
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anna342
Member
Registered: March 2007
Location: England
Posts: 95
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Review Date: Mon November 5, 2007
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 6
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Pros:
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Helped with sleep
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Cons:
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Hangover feeling and took a while to work
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It did work well for the purpose- Insomnia- however I'd feel tired all day. Also took a larger dose than I thought have, and gave me a terrible hangover. My own fault I know!
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haleyshea
Newly Joined
Registered: December 2007
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Review Date: Tue December 4, 2007
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 4
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Pros:
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gets you to sleep fast
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Cons:
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nightmares, inabilitly to wake from nightmares, grogginess
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I was prescribed this medicine to help me get to sleep, but the side effects were too bad.
I would have very terrifying dreams and even once I realized I was dreaming I could not wake up. The next morning I would always feel hung over and sore.
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BLMr81
Newly Joined
Registered: December 2007
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Review Date: Fri December 28, 2007
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 3
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Pros:
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Slept very well
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Cons:
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Couldn't think clearly
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Though it did help me sleep, like it was prescribed for. I wasn't warned about dementia like side effects, which I had.
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Ben23
Newly Joined
Registered: February 2008
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Review Date: Wed February 13, 2008
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 8
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Pros:
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Helps a lot for sleeping problems, calms down (sort of)
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Cons:
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Grogginess (1-2 strong coffees needed in the morning), difficulty concentrating, effects wears off with time, reeeeaaaally dry mouth/sore eyes
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Great med to help solve temporary sleep problems. I started Paxil 10mg and was unable to get more than 2-3 hours of sleep for several days... GP prescribed this, made me sleep 8-9 hours for a few days... Then more 5-6 hours, but still, helps a lot. Stopped when the Paxil "kicked in" but still use it some days where I feel I won't get a good night sleep.
Btw, as I said I am on Paxil 10mg and I don't know if the side effects were caused by the Trazodone or worsened by it (from the Paxil)... But definatly, this is a life saver for insomniacs and the side effects are nothing (to me, at least) compared to the benefits of a 6+ hours night.
Oh yeah, I switched from Rivotril (clonazepam) to this without any problems (tapered off a few days though, 1mg --> 0.5 mg (4-5 days) --> 0,25mg (4-5 days)). More effective than any benzo I've tried (for sleep problems, that is) and less addictive.
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apbutterfly
Newly Joined
Registered: February 2008
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Review Date: Fri February 15, 2008
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 7
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Pros:
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a little calmer
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Cons:
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very groggy first few days
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I was placed on trazadone due to severe insomnia and depression.
I had been off meds for a long time because I foolishly thought I could do without them. I have been such a wreck because of that.
The first 3 days I was extremely groggy. I had a hard time getting out of bed. Drowsy all day. At night I could only sleep in 2-3 hour increments. And more times than not I could not return to sleep after waking. I eventually had to start taking 2 50 mg tabs at night along with 4 tylenol pm and 2 benadryl to be able to sleep and stay asleep.
I have been on it now for 3 weeks, I feel a little better but still having a lot of the intense negative feelings that drove me back to medication in the first place.
Note: I am severely depressed and it never seems to go away. I have been hospitalized numerous times for it and also due to self mutilation. And also currently on along with the trazadone, zyprexa and zoloft.
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butaflikim
Newly Joined
Registered: February 2008
Location: Louisiana
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Review Date: Sat February 23, 2008
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Would you recommend the product? Yes |
Total Spent: $4.98| Rating: 10
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Pros:
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I fall into a deep sleep, Works well with my Lexapro
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Cons:
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First few nights i had the hangover effect
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I was on lexapro for about a month and a half and i couldnt sleep at all and it only made me feel about 50% better. my dr then prescribed trazadone to help with the insomnia and after only about a week it was working wonders. i had a little bit of a hangover the first few night but now i am fully rested in the morning and my mood has improved greatly
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Hombo
New Member
Registered: March 2008
Location: Alberta
Posts: 1
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Review Date: Mon March 10, 2008
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 8
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Pros:
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Helped with sleep, relaxed me in the evenings.
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Cons:
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Bad headaches, intense drowsyness, impossible to wake during sleep.
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Prescribed in hospital treatment. Not addictive, affordable, and really helps with sleep.
Especial calming effect helps with anxiety.
Hard to wake up once asleep; early mornings difficult.
Over all effect: better rest leaves you in a better state of mind, making it a good choice.
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jp__
Newly Joined
Registered: May 2008
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Review Date: Fri May 2, 2008
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 10
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Pros:
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Helps with anxiety and sleeplessness
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Cons:
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none
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I was prescribed this because my night terrors had returned. Medicine Dr. thinks it is because my AM depression pill (Celexa) wears off by bedtime. I take Trazodone in the PM about 4:30 p.m. I am usually ready to sleep by 8:00 p.m. which is a good turnaround. Since started taking Trazodone i have not had any night terrors. Previous reviewers have mentioned that this drug does have a hangover effect. Their statements are true, but I will gladly endure the hangover effect because Trazodone has helped my symptoms drastically.
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modernmaster
Newly Joined
Registered: May 2008
Location: Central,va
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Review Date: Mon June 30, 2008
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Would you recommend the product? Yes |
Total Spent: None indicated| Rating: 7
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Pros:
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mild anti-depressant , sleep aid & calming
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Cons:
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headaches must take with clonazepam ,bad taste
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Dreams really wild & vivid, has some pain relief, no sexual problems
& has off label use cocaine cravings.Handy for someone I know real well.
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LLMF
New Member
Registered: July 2008
Location: Wisconsin
Posts: 4
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Review Date: Tue July 8, 2008
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 4
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Pros:
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Knocked me the $@&* out!
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Cons:
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Felt brain dead the entire next day and part of the day after that.
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although at a 100mg it did make me fall asleep after 1.5 hours, the next day I felt brain dead. I couldn't get joy out of anything and I had no motivation. It's as if I couldn't think more than 1 or 2 steps ahead of anything...
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Grunt49
Newly Joined
Registered: July 2008
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Review Date: Fri July 18, 2008
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Would you recommend the product? No |
Total Spent: None indicated| Rating: 2
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Pros:
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Not good
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Cons:
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all bad
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Door a VA put me on this crap to treat PTSD.
I was taking 4 100mg tabs a night. Wild Nightmares and dreams drowsy all day gained 60 lbs in 8 months.
I get tired of this crap and head to a civilian using tricare. he immediatly said the guy was a quack and cut it down to 100 mg and then took me off. The bad thing is he had me taking up to 700MG a day which the new doc said could have put me in a permane | | | |
;)
